The La Vida Edge
Why We Use 350 Million MSCs in Intravenous Therapy
At La Vida Stem Cells, we utilize a high-dose intravenous (IV) mesenchymal stem cell (MSC) protocol of 350 million cells. This dosing strategy is based on international clinical research, biological rationale, and real-world safety data from outside the United States.
Our goal is simple: to deliver a therapeutically meaningful dose that maximizes systemic anti-inflammatory and regenerative signaling—while remaining aligned with globally studied safety standards.
What Makes Our IV Dose Different
Most IV stem cell treatments worldwide use relatively modest cell counts. However, growing international evidence shows that higher IV doses produce stronger biological effects, particularly for chronic, systemic, and inflammatory conditions.
La Vida’s 350 million MSC IV dose places patients at the upper end of internationally studied dosing ranges, offering a more robust therapeutic opportunity.
International Clinical Basis for the 350M Dose
Outside the United States, multiple clinical trials and hospital-based protocols have explored IV MSC dosing in the range of 1–5 million cells per kilogram of body weight.
For an average adult:
- 5 million cells/kg ≈ 350 million cells
This upper range has been studied in:
- Autoimmune and inflammatory diseases
- Neurologic and neurodegenerative conditions
- Pulmonary and systemic inflammatory disorders
- Chronic degenerative conditions
Across these studies, high-dose IV MSC therapy has demonstrated favorable safety profiles, with no consistent dose-limiting toxicities reported.
Our 350M protocol is intentionally aligned with this international upper benchmark.
Why Higher IV Doses Matter
- 1
First-Pass Pulmonary Effect
When MSCs are delivered intravenously, a significant portion is naturally filtered through the lungs. This is a known and expected biological phenomenon. A higher initial dose helps ensure that enough viable cells remain active to exert systemic benefit.
- 2
Dose-Dependent Immunomodulation
International studies consistently show that higher MSC doses correlate with stronger anti-inflammatory signaling, including:
- Reduction in pro-inflammatory cytokines
- Increased anti-inflammatory mediator activity
- Improved immune system regulation
- 3
Systemic Conditions Require Systemic Dosing
Chronic conditions—especially autoimmune, neurologic, and multi-joint degenerative diseases—often involve widespread inflammation. A high-dose IV approach is designed to address the body as a whole, not just a single area.
What Conditions Benefit Most from a 350M IV Protocol
Our high-dose IV strategy is commonly utilized as a foundation for patients with:
- Autoimmune and inflammatory disorders
- Neurodegenerative conditions (such as Parkinson’s-related syndromes)
- Chronic pain involving multiple joints or body systems
- Post-viral or immune dysregulation syndromes
- Metabolic and systemic inflammatory conditions
In many cases, the IV infusion is combined with targeted procedures (joint injections, epidurals, or other localized therapies) for a comprehensive regenerative approach.
Safety Considerations
High-dose IV MSC therapy has been explored internationally with careful monitoring. Reported adverse events in published studies are generally mild and transient, such as:
- Temporary fever
- Fatigue
- Short-lived infusion reactions
At La Vida, all patients undergo medical screening and physician evaluation prior to treatment to ensure appropriateness and safety.
Our Philosophy
We believe that dosematters.
Providing too few cells may limit biological impact—especially in patients who have lived with chronic inflammation or degeneration for years. By offering 350 million MSCs intravenously, we aim to give patients a clinically meaningful dose grounded in international science, not guesswork.
A Personalized Approach
While 350 million MSCs is our standard IV protocol, every treatment plan is individualized. Your physician may recommend additional localized procedures or supportive therapies based on your condition, goals, and medical history.
Schedule a Consultation
If you would like to learn whether high-dose IV stem cell therapy is appropriate for you, our medical team is available to review your case and discuss treatment options.
